[ Diabetes Solutions ]

Commentary: Protect your eyes from diabetes

The pressure inside the eyeball (the intraocular pressure) is naturally maintained by a continuous flow of liquid called aqueous humour through the eyeball. This can be due to autoimmune damage to the pancreas (Type 1 diabetes), or due to decreased effects of insulin (a natural hormone in the body that regulates blood sugar concentrations) due to poor diet, such as in the much more common Type 2 diabetes. Insulin is a hormone that regulates blood sugar. During a diabetic eye exam, our on-staff optometrists, Dr. Because of this, many regard the retina as an extension of brain tissue. The Stages of Diabetic Retinopathy Non-proliferative stage: The non-proliferative stage is also known as background diabetic retinopathy. Instead, it sees the light that objects reflect.

Blood sugar and blood pressure control are the most important factors in preventing diabetic damage to the eye. Diabetic retinopathy begins when the walls of small blood vessels in the retina weaken. Preventive Services Task Force recommends vision screening for all children aged 3 to 5 years to find conditions such as amblyopia, or lazy eye, which can be treated effectively if caught early. When blood glucose builds up, the blood vessels inside the retina may be damaged – this is called diabetic retinopathy. Another 8.1 million people, nearly 28 percent of the population, are estimated by the CDC to be undiagnosed diabetics. This is to minimise the amount of travoprost that may be absorbed into the bloodstream

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[ Nutrition ]

[Bioenergetics of liver mitochondria after administration of ramipril in experimental diabetes mellitus]. – PubMed

In a new study entitled “Loss of mitochondrial pyruvate carrier 2 in liver leads to defects in gluconeogenesis and compensation via pyruvate-alanine cycling,” scientists discovered a key protein in livers mitochondria – mitochondrial pyruvate carrier 2 (MPC2) – that controls glucose synthesis and is a potential target for new diabetes therapies. If this were true in the world of biology, then diabetes and mitochondrial disease could become besties. Aging of diabetic mice induced a decrease in brain mitochondrial RCR, ADP/O, and ATP/ADP ratios but induced an increase in the repolarization lag phase. Endothelial mitochondria are mainly responsible for generation of reactive oxygen species (ROS) and maintaining the Ca(2+) concentration in the cytosol. Sprague-Dawley male rats were injected ip with streptozotocin to induce diabetes. (8) examined the associations among chronic free fatty acid (FFA) levels, intramyocellular lipids, the capacity for skeletal muscle mitochondrial ATP production and IR in human obesity and T2D. Naringenin, a flavonone, exerted anti-hyperglycemic effect and was able to prevent oxidative stress and resultant apoptotic events caused due to diabetes-induced hepatotoxicity.

Rat islets were cultured in vitro for 2-3 weeks at 27 or 11 (control) mmol/l glucose. The correlation between oxygen consumption and nitroglycerin-mediated dilation may suggest a link between mitochondrial dysfunction and vascular smooth muscle cell dysfunction that

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[ Diabetes Type 2 ]

Otitis externa – Diagnosis – History & examination – Best Practice


Chronic obstructive pulmonary disease (COPD) exacerbations admitted in intensive care units (ICUs) occur rarely due to fungal respiratory tract infections, but may occur when associated co-morbidities like diabetes mellitus coexist. The most important risk factors include neutropenia or functional neutropenia, diabetic ketoacidosis, iron overload, major trauma, prolonged use of corticosteroids, illicit intravenous drug (ID) use, neonatal prematurity, malnourishment, and maybe a previous exposure to antifungal agents with no activity against zygomycetes, such as voriconazole and echinocandins.A high index of suspicion is crucial for the diagnosis, as prompt and appropriate management can considerably reduce morbidity and mortality. He reports no other symptoms. Debridement of an staphylococceal infected hematoma through a single left lateral gluteus incision, and primary closure was performed. The ability to anticipate treatment outcome is a critical part of risk management in an implant practice. Several isolated cases of pneumonia, bacteremia, endocarditis, endometritis and peritonitis were observed. The patient underwent surgical debridement, resulting in a wound 7 cm x 4 cm, and was provided ceftriaxone 2.0 g intravenously daily along with insulin therapy.

A 72-year-old nonsmoker male, known case of diabetes mellitus type II since 10 years, on oral hypoglycemic agents, presented with the complaints of altered sensorium with low-grade fever associated with pain

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