[ Diabetes Solutions ]

AstraZeneca falls on diabetes worries

Insulin, a lifesaving treatment for diabetes, was first patented in 1923. It’s exactly the kind of everyday problem that drives parents of diabetic kids batty. The development of new medicines is particularly important for minorities, including Latino residents. Dr. In the multiple dose study, MGL-3196 demonstrated proof-of-concept for lipid lowering including dose-dependent, highly significant, up to 30% lowering of LDL cholesterol and non-HDL cholesterol, and a strong trend of up to 60% triglyceride lowering. senior director, insulin marketing. The inflation rate in South Africa was reported at 5,3% in August 2011.

Later this year, the company expects to seek approval for an unnamed drug that combines Januvia with the common diabetes medication metformin, which would reduce the number of pills patients take daily. Gilead’s major drugs include Harvoni and Sovaldi for Hepatitis C, Tamiflu, and Macugen for age-related macular degeneration. Studying under Sutherland’s guidance, the elder Geho learned the foundation of knowledge that he’d go on to use in developing liver-specific insulin many years later. Sanofi strengthens ties to the government by offering diabetes training; Novo retaliates by promising more local education, research and manufacturing. Anglo American, up 25½p at £11.29, led the risers in the FTSE 100, bolstered by rising metals prices and vague trader speculation the miner was being eyed by predators for a break-up. When people

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[ Nutrition ]

Comment on Sjöholm et al. Weight Change–Adjusted Effects of Gastric Bypass Surgery on Glucose Metabolism:

A study compared two-year outcomes between conservative management (intensive lifestyle and medical management) and surgical management (lifestyle and medical management plus Roux-en-Y gastric bypass surgery. A research team led by Nicholas Stylopoulos, HMS assistant professor of pediatrics at Boston Children’s Hospital, has identified the small intestine—widely believed to be a passive organ—as the major contributor to the body’s metabolism, based on a study in rats. I asked him why. As someone who has been investigating the link between gastrointestinal surgery and glucose homeostasis since the late 1990s, I have witnessed first-hand how getting to this point has required many clinical scientists to put aside long-standing preconceptions. The postprandial incretin effect on insulin secretion, blunted in diabetes, improves rapidly after the surgery. She reported a history of truncal obesity and thin extremities throughout her life. Researchers measured participants’ fasting blood sugar and insulin levels, sensitivity to insulin, body weight, waist circumference, body composition, blood pressure, cholesterol, aerobic fitness, medication usage and quality of life before the study began, after six months and after 12 months.

When performed in high-volume centers by expert surgeons, RYGB has a similar rate of overall complications and lower rate of reoperations than LB. Weight loss associated with laparoscopic gastric bypass significantly improves diabetes control

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