[ Nutrition ]

Risk factors for sudden death and cardiac arrest at the onset of fulminant type 1

Impaired arterial baroreflex sensitivity (BRS) has been associated with cardiac mortality and non-fatal cardiac arrests after a myocardial infarction. The person was observed to be in good health before going to bed. Circumstances of death, psychiatric diagnoses, psychotropic drugs, and past medical history were extracted from the root cause analyses of sudden, unexpected deaths. Greene HL, Richardson DW, Barker AH, Roden DM, Capone RJ, Echt DS, Friedman LM, Gillespie MJ, Hallstrom AP, Verter J. This can be accomplished by promptly initiating ACE inhibitors, angiotensin receptor blockers, beta-blockers, antiplatelet agents (aspirin), and possibly statin therapy for CAD, hypertension, and/or hypercholesterolemia. Without defibrillation within minutes, this type of event is fatal. Blood flow is increased to the myocardium, splanchnic circulation and the brain.

Some evidence to the contrary also exist as in the Paris Prospective Study diabetes was associated with increased risk of SCD but not for increased risk of non-fatal myocardial infarction [9]. Nakagawa M, Abe S, Tsutsumi R, Goto D, Tsutsu N, Umeno J, Inou T. Cases of sudden death were also more likely to have received blood transfusion within the previous 1 year. Poor glycemic control was strongly associated with sudden cardiac death in diabetic hemodialysis patients, which accounted for increased cardiovascular events and mortality. 2004;47:671 (in Japanese). We will conclude by highlighting important areas for further research to identify and treat those at risk of SCD. Fulminant type 1 diabetes mellitus with cardiopulmonary arrest.

J Japan Diab Soc. 2005;48:371 (in Japanese). Kobayashi T, Isomine S, Goto M, Sato M, Kanazawa T, Sakaida K, Iwaoka H. (15) provide a pessimistic view of the utility of on-site automatic external defibrillators (AEDs) in dialysis centers, reporting a 1-yr Kaplan-Meier survival estimate of 9.5% after cardiac arrest in Gambro centers with AEDs on-site (n = 237 patients in 140 clinics) and 7.8% in sites without AEDs (n = 492 patients in 254 clinics). J Jpn Soc Intensive Care Med. 2005;12:25–30 (in Japanese). Shibasaki S, Imagawa A, Tauriainen S, Iino M, Oikarinen M, Abiru H, Tamaki K, Seino H, Nishi K, Takase I, Okada Y, Uno S, Murase-Mishiba Y, Terasaki J, Makino H, Shimomura I, Hyoty H, Hanafusa T.

Expression of Toll-like receptors in the pancreas of recent-onset fulminant type 1 diabetes. [Arrhythmic means any variation of the normal regular heartbeat.] They point out that dysrhythmias can occur with early autonomic neuropathy, with relative sympathetic overactivity, in young people with diabetes. 2010;57:211–9. Standardization of the oral glucose tolerance test. Sudden cardiac death: influence of diabetes. J Japan Diab Soc. 2010;53:S207 (in Japanese).

In a recent systematic review with follow-up times of individual studies ranging from 5 to 21.5 years, the pooled relative risk of fatal and non-fatal cardiac events associated with IGT was 1.20 (95 % CI 1.07–1.34) but the degree of adjustment was limited in many of the included studies [22]. A case of ischemic stricture of the small intestine due to cardiac arrest caused by diabetic ketoacidosis in fulminant type 1 diabetes. J Japan Diab Soc. 2011;54:356–60 (in Japanese). Maekawa Y, Yara T, Nashiro K, Masuda F, Kowatari M, China Y, Yamashiro A, Kinjyo M, Shiroma I. A survived case of fulminant type 1 diabetes after cardiac arrest with hyperkalemia and ST elevation. J Japan Diab Soc.

2011;54:359 (in Japanese). Ro A, Hisashi Y, Kageyama N, Tanifuji T, Hayashi K, Fukunaga T, Fujita MQ. Two autopsy cases of sudden death in adolescent by fulminant type 1 diabetes mellitus. For example, examining the benefit of cardioprotective agents such as β-blockers would be reasonable in dialysis patients without manifest heart disease (who, “unfortunately,” have a lower event rate, driving up the sample size needed for adequate power). 2006;12:22–6 (in Japanese). Kashiwagi A, Kasuga M, Araki E, Oka Y, Hanafusa T, Ito H, Tominaga M, Oikawa S, Noda M, Kawamura T, Sanke T, Namba M, Hashiramoto M, Sasahara T, Nishio Y, Kuwa K, Ueki K, Takei I, Umemoto M, Murakami M, Yamakado M, Yatomi Y, Ohashi H. International clinical harmonization of glycated hemoglobin in Japan: from Japan Diabetes Society to National Glycohemoglobin Standardization Program values.

J Diabetes Investig. 2012;3:39–40. Nishida W, Hasebe S, Kawamura R, Hashiramoto M, Onuma H, Osawa H, Makino H. A case of fulminant type 1 diabetes associated with high titer of coxsackie B3 virus antibody. Nat Rev Cardiol. 2005;48(suppl 1):A23–7 (in Japanese).

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