[ Nutrition ]

Prevalence of diabetes mellitus secondary to pancreatic diseases (type 3c). – PubMed

With the evidence in hand that tight glycemic control can prevent long-term complications of diabetes mellitus1,2 and the ability to measure and monitora person’s blood glucose levels at a moment’s notice, a new medical concept and burgeoning industry spawned in just a few years. Chronic diseases are the leading causes of fatal burden of disease (the amount of life lost due to people dying early) in most age and sex groups [1] and are the leading cause of illness, disability and death in Australia, accounting for 90% of all deaths in 2011 [2]. For this purpose, we studied 36 children with normal small-bowel mucosa and 26 children with active CD, including 12 patients with T1D. In this study, we investigated 1868 patients diagnosed with diabetes mellitus who had been admitted to our hospital during the last 24 months. Diabetes mellitus is highly prevalent, it results in tremendous costs (a significant portion of which are preventable), and it can be easily measured. 861,057 Australians were alive in 2009 who had been diagnosed with cancer in the previous 28 years [4]. In contrast, no significant differences were found in IgA or IgG antibodies specific for bovine beta-lactoglobulin or Bifidobacterium adolescentis DSM 20083-derived proteins.

Thus, diabetes mellitus due to chronic pancreatitis occurred in this collective in 7.2% of all diabetic subjects. A retrospective study of 2 years of claims data from an integrated healthcare system found that patients with diabetes enrolled in their disease management program had average claims of $394.62 per patient per month compared with $502.48 per patient per month for those with diabetes but not enrolled in the  program.8 According to the researchers, the system saw a return on investment (ROI) of 2.23:1 (that is, $2.23 of savings accrued for every $1.00 invested);  others question this result based on the cost calculation.9 Furthermore, this magnitude of savings could not be demonstrated by others. From 1977–2010 there has been an overall decrease in the average number of permanent teeth affected; however there has been a gradual increase from the late 1990s [9]. Most type 3 diabetes patients were initially misclassified as type 2 diabetes (69/84). Diabetes mellitus secondary to pancreatic diseases (especially chronic pancreatitis) seems more common than generally believed with a prevalence of 9.2% among the subjects studied here. As mentioned earlier, disease management programs were designed as secondary prevention programs, meaning that eligible patients were already subject to repeat ED visits or hospitalizations, and were already being treated (perhaps not optimally). A common problem seems to be the differentiation between type 2 and type 3.

Yet, the right classification of diabetes mellitus is important, because there are special therapeutic options and problems in patients with diabetes secondary to pancreatic diseases.

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