The pancreas’ function is to product insulin for the body. The authors compared results and morbidity in insulin-dependent diabetes mellitus (IDDM) patients undergoing preemptive pancreas transplantation (PTx) either before dialysis or before the need for a kidney transplant with IDDM patients undergoing conventional combined pancreas-kidney transplantation (PKT) after the initiation of dialysis therapy. In general, patients of advanced age are not accepted for pancreas transplant or combined kidney and pancreas transplant. At a mean follow-up of 24 months we found no significant difference between the groups in the rate of progression of retinopathy, expressed as a score. A lack of insulin causes diabetes. There were no significant differences concerning fasting glucose, HbA1(c), glucose tolerance and renal function between the groups. We report that diabetic glomerulopathy lesions, unchanged at 5 years post pancreas transplantation, significantly improved after 10 years, with complete normalization of glomerular structure in most patients.
It was concluded that an alkalemic pH does not rule out the presence of ongoing DKA. An organ transplant recipient usually needs to take immunosuppressants for the rest of his or her life. The latter two are related to pancreatitis, duct disruption, or leak from the duodenojejunostomy. ▲280 cases received cadaveric donor pancreas transplantation and ▲20 cases received living-donor pancreas transplantation.