Most people need about 6-8 glasses of water each day. Treated ZDF rats exhibited consistently lower blood glucose levels than vehicle-treated diabetic controls, with a delayed rise and lower plateau levels. Carvacrol at the doses of 25 and 50 mg/kg body weight were orally administered to diabetic rats for a period of 7 days after the onset of diabetes. Factors that must be considered in selecting a biomarker for a given study include the objectives of the study, the availability and specificity of potential markers, the feasibility of measuring the markers (including the invasiveness of the necessary techniques and the amount of biological specimen needed), the time to appearance and the persistence of the markers in biological media, the variability of marker concentrations within and between individuals, and aspects (e.g., cost, sensitivity, reliability) related to storage and analysis of the samples (Vine 1994). Blood glucose and lipid levels, body weight, the amounts of food consumption, and water intake were determined in all groups at weeks 0 (before diabetes induction), 3, 6, and at the end of eighth week. Example 180 lb = 90 oz. When my first Maltese was a puppy, he was hospitalized for dehydration as a result of not having access to water for too long a period.
The changes in average food intake were reasonably consistent with the “utilizable fuel” theory for the control of food intake assuming that the CHO component of each diet was non-utilizable.