[ Diabetes Type 2 ]

Obstructive sleep apnea and type 2 diabetes: is there a link? – PubMed


There is convincing evidence that, in humans, discrete sleep stages are important for daytime brain function, but whether any particular sleep stage has functional significance for the rest of the body is not known. For the unfortunate nurses who reported having sleep apnea, sleeping fewer than six hours, and often working the graveyard shift in addition to sleeping difficulty, that risk increased more than four-fold. Subjects were followed until 1996 for the diagnosis of diabetes (1,969 cases). “In this short-term study, we found that two long nights spent catching up on lost sleep can reverse the negative metabolic effects of four consecutive nights of restricted sleep,” Josiane Broussard, assistant research professor at University of Colorado, Boulder noted. In a large trial conducted in patients’ homes in the US and Canada, scientists demonstrated that they could predict and prevent dangerously low overnight blood sugars in adolescents and adults with type 1 diabetes. Their average age was about 40. However, there are currently no studies that determine the causal direction of this relationship, nor whether sleep interventions are likely to offer benefit for people with diabetes to help them achieve tighter glucose control.

Increased levels of cortisol affect the body�™s ability to properly metabolize glucose and release insulin. Furthermore, our data suggest that reduced sleep quality with low levels of SWS, as occurs in aging and in many obese individuals, may contribute to increase the risk of type 2 diabetes. More data from large-scale longitudinal studies with rigorous assessments of diabetes and OSA are needed. Avoid oversleeping on weekends where teens struggle to get back into the sleep routine on Sunday nights. But there were no significant differences between those who had OSA and those who didn’t in terms of gender, BMI, total daily insulin dose, HbA1c, or, interestingly, by smoking status (35% of the total group were smokers; 17% of those with OSA smoked vs 15% of those who didn’t develop the condition). As expected, those in the treatment group had improvements in daytime sleepiness and maintenance of wakefulness test results.

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