[ Nutrition ]

Nutrition Journal

But portion control isn’t easy. To do that takes more than choosing the right foods. It’s good to keep in mind that you’re in control of the portions you eat, whether you’re at home, dining out, or visiting family or friends. * Low-salt Foods – Salt is a mineral that is helpful to the body, if used sparingly. Unexplained weight gain? The Plate Method Of all the tactics for keeping portion sizes in check, the plate method is the easiest—hands down. The use of the hand.

In other words, the bean group was asked to eat more food and the cutting calories group was asked to eat less food. The question of alcohol Inevitably, there will be diabetics who will wonder whether alcohol is still safe to drink. Eat a baked sweet potato rather than an Irish potato with your dinner. However, Americans’ average daily calorie intake has risen from about 1800 to 2000 over the past 20 years, and restaurants have switched from 10-inch plates to 12-inch plates. Objective: To compare patient compliance and benefits, over 12 months, of 1 versus 2 partial meal replacement (PMR) for the management of overweight/obese subjects with inadequately controlled type 2 diabetes. Also, documenting adherence in daily logbooks was only required in the PC group, and patients in the PC group may have been more worried about what they were eating because they were using logbooks. At baseline, a lecture titled, “What is diabetes and its complications?” by diabetic educators and, “Eating healthy with diabetes” by registered dieticians (RD) was offered to the subjects.

Then, add unlimited amounts of vegetables and salad. Medifast was developed at the prestigious Johns Hopkins University to help overweight surgery patients lose weight prior to surgery. Don’t worry. It allows unlimited vegetables with the exception of peas, carrots, corn and potatoes. “These medications can work in several different ways,” says Weinstein. When eating out, share an entrée with your dining companion. It is 27.4 cm long, 21.0 cm wide and 2.5 cm deep.

Three-sixths (one-half) of the plate was labeled “vegetables”, one-sixth was labeled “rice, bread and noodles” and two-sixth were labeled “fish, meat, chicken and nuts”. One section was similar to 1 unit (= 80 kcal) of the food exchange list. The subjects were instructed to use the plate for their largest meal of the day and encouraged to use the plate for all meals. The food-craving inventory (FCI) measured general cravings (total score) and cravings for the following specific types of foods: sweets, high fats, carbohydrates/starches, fruits/vegetables, and fast-food fats (9). Lecture: “Tips to reduce body weight with a healthy plate” and “What is carbohydrate control?” by dietitians. Lunch using the healthy plate. Discussion.

At baseline, a lecture titled, “What is diabetes and its complications?” by diabetic educators and, “Eating healthy with diabetes” by a RD was offered to the subjects, similar to the intervention group. After this initial lecture, the subjects in the control group were advised to continue their routine health care at each clinic. The nutrition experts ate about 15 percent more ice cream than those who used the 2-oz spoons. All measurements were conducted in the same order for all subjects in the intervention and control groups at the baseline and after the 3-month intervention period. We instructed the subjects not to participate in vigorous physical activity or to consume alcohol within the 24 hours prior to the measurements. They can increase appetite and promote weight gain. For both measurements, the subjects wore only underwear and were barefooted and they had been fasting for at least 8 hours.

The BMI was calculated as weight (in kilograms) divided by height (in meters) squared. According to Odilia Bermudez, Ph.D., of Tufts University, soft drinks and other sugar-added beverages have overtaken white bread and are now the main source of calories in the average American’s diet. The abdominal circumference measurements were taken in duplicate to the nearest 0.1 cm, and the averaged value was used for the analysis. The following clinical data, blood pressure, serum lipids (total cholesterol, low-density lipoprotein [LDL]-cholesterol, high-density lipoprotein [HDL]-cholesterol, triglycerides), creatinine (estimated glomerular filtration rate as calculated by creatinine), aspartate aminotransferase (AST), alanine aminotransferase (ALT), γ-glutamyltransferase (γGT), plasma glucose and hemoglobin A1c (HbA1c), were measured at a central laboratory (Okazaki Medical Association Public Health Center, Aichi, Japan). In many cases, I could make relatively simple modifications to favorite dishes that still preserved their taste and essence. The levels of appetite, dietary satisfaction and distress related to the diet were recorded using 100 mm visual analogue scales (VAS). An integrated appetite score was especially calculated as the score: VAS hunger + VAS prospective consumption + (100-VAS gastric fullness)/3 [23].

The desire levels to eat sweet, salty, spicy and rich foods were also recorded using the VAS. Use a post-it note on the refrigerator or anywhere it is visible to you. The profile of mood states (POMS) test in a brief version is composed of 30 questions with a 5-point scale about the current mood state, which is classified into “tension-anxiety”, “depression-dejection”, “anger-hostility”, “vigor”, “fatigue” and “confusion” subscales [26, 27]. A low POMS score indicates a better mood state, except for the “vigor” factor. Information on the use of anti-diabetic agents was also recorded during the intervention. Participants were asked “How often did you use the healthy plate per day during the intervention?” at the end of the study. Responses were classified as one, two, and three times per day.

We did not monitor the use of the healthy plate every day during the intervention. After the intervention, a trained researcher independently interviewed each subject in the intervention group regarding their impression of the intervention, including satisfaction with the intervention, using a structured questionnaire. Dietary intake and walking steps were measured only in the intervention group. Dietary intake was assessed using standardized software for population-based surveys and nutrition counseling in Japan (EIYO-KUN v.6.0, developed by Shikoku University Nutrition Database) based on the Standard Tables of Food Composition in Japan [28, 29]. Steps were counted using a pedometer (Omron HJA-307IT; Omron Corporation, Kyoto, Japan). It can be managed through exercise, proper eating habits, portion control, and modern medicine. A sample of 18 subjects was calculated calculation based on detecting a difference of 3 kg and a standard deviation (SD) of 2 kg in weight loss at the 3 month follow-up between intervention and control group, with 80% power and 5% significance.

The difference (plus SD) was based on a previous study that examined weight changes with a lifestyle modification, similar to the current study [19]. The sample size was calculated using StatMate software.

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[ Diabetes Type 2 ]

Nutrition Journal

Hi Kitten, I agree with linda that the first thing you should do is a pregnancy test – if you can buy an at-home one you can have the answer really soon, and otherwise go to your doctor or a clinic and have them test. Then you probably know your period can be more like your flaky friend who always shows up late to drinks (and sometimes not at all) than that super-organized friend who’s early to every group dinner. See a doctor should it take more than a year to adjust or if your last period was more than 6 months ago. The reason I ask is because I think Metformin may be delaying my menopause. If you suddenly can’t keep your eyes open and are extra fatigued, you might be pregnant . Usually, menstrual cycle repeats for every 28 days. These relationships were strong, graded, and independent of socio-demographic factors, baseline risk factor values, and co-morbidities.

Too often, people are told their results are “normal” when in fact, closer examination may show that their results are borderline (and should be watched and retested later) or are actually abnormal when using the newer, lower cutoffs. Hormonal fluctuations and the overproduction of particular hormones called androgens can lead to acne by overstimulating the sebaceous glands, which produce the skin’s natural oils. Stress, medical conditions such as diabetes and tuberculosis, and eating disorders all play havoc with our periods, as does travel. in 2014, [24] probably explains these findings. This can cause missed menstrual periods. With classical CAH this enzyme is missing, which means your adrenal glands can’t make these hormones. The amount of soy is equivalent to the amount in 500 milliliters of soymilk.

Missed or irregular menstrual cycles are the first clue. So if could someone please tell me what’s going on? As noted earlier, you’ll know you are there on the day that 12 consecutive months have passed without a period. You may need to use back-up birth control, such as condoms or a spermicide, when you first start using this medication. Follow your doctor’s instructions. Do not take 2 doses at once. Follow your doctor’s instructions.

The studies performed on humans are few, but they have been consistent in demonstrating that SR reduces postprandial blood glucose and improves medium term glycaemic outcomes. When the pills run out, start a new pack the following day. Use back-up birth control for at least 7 days following the missed pills. Therapy with Wellbutrin may be resumed 24 hours after the last dose of linezolid or intravenous methylene blue. Two studies explored the use of SR on patients with pre-diabetes [30] and drug naïve mild type 2 diabetes patients [28] in placebo controlled trials of 6 week duration. A randomized double blind placebo controlled study explored the effectiveness of tea containing SR on glycaemic control in type 2 diabetes patients over a 3 month period using a cross over design [29]. You do not need to use a backup method of birth control if you only miss 1 pill.

Risperidone may raise your blood sugar. Any doctor or surgeon who treats you should know that you are using Ortho Tri-Cyclen. On Sunday, throw out the rest of the pack and start a new pack that day. If you need surgery or medical tests or if you will be on bed rest, you may need to stop using Yaz for a short time. This may be due to the short duration of the treatment arms lasting only 6 weeks, which may be inadequate to demonstrate a fall in HbA1C. Jayawardena et al. Hyperthyroidism is characterized by heart palpitations, weight loss, intolerance of heat, and increases in appetite, sweating, and bowel movements.

Still not sure what is the cause of your missed periods? Shivaprasad et al. demonstrated S. reticulata treated individuals had significant improvement of fasting plasma glucose levels, but having no significant effect on an OGTT. To assess potential confounding factors, simple linear regression was used to determine the association between outcome measures (final A1c, SBP, and LDL) and demographic and clinical exposures, including co-morbidities. So postpartum thyroiditis tends to be underdiagnosed and the incidence may be higher than generally acknowledged. The results from the study by Shimada et al.

also suggests the SR selectively improves metabolic derangements of obese individuals but not that of healthy non-obese ones. Obese individuals have mature and hypertrophic adipocytes, leading to metabolic derangements. Hitherto, the effect of SR on these cells was not known, but the results of the Shimada study [24] is conclusive in demonstrating normalization mesenteric and adipocyte hypertrophy and increasing adiponectin secretion. At present these findings are limited to animal models and need to be explored in future human studies. Ability of complementary medicines to have significant hypoglycaemic effect when used in isolation or when used at higher plasma glucose concentrations together with other oral agents levels has been reported [5]. This is probably attributable to their weak hypoglycaemic effects being masked by the more potent oral agents used in the treatment of diabetes. However Salacia showed significant improvement in glucose handling of both treatment naïve pre-diabetic patients as well as those on oral agents [29,30].

The contribution of postprandial glycaemia to hyperglycemia has been shown to decrease as HbA1c increased in type 2 diabetic patients. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. In addition the methods utilized for extraction of the plant material (methanol or aqueous extraction), the particular component of the plant that’s used (E.g. stem, root, leaf) and the dose of extract used varies widely between studies.

This makes interpretation of results more difficult. Indeed this remains a common problem in interpretation of trials that utilize traditional no-proprietary complementary medicines globally [5].

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[ Diabetes Type 1 ]

Nutrition Journal

BACKGROUND: Diabetes mellitus (DM) is a metabolic disorder that is associated with an increased risk of cardiovascular disease. Bilberry is a low growing shrub and the fruit as well as the leaves of this plant have been used for medicinal purposes for centuries. And an unassuming little berry known as the bilberry has a special affinity for the vascular system, helping to promote and maintain health throughout the entire body. According to legend, British Royal Air Force pilots reportedly ate bilberry jam during World War II to improve their night vision, although there is contradictory evidence about the effectiveness of bilberry for improving night vision. Movement during the 300 min OGTT was kept to a minimum. AMPK stimulates fat breakdown in liver and muscle, and modulates insulin secretion by the pancreas. For a 2001 report in Alternative Medicine Review, investigators sized up the available research on natural therapies for diseases of the eyes.

Prost Leuk Essen Fat Acids. The extracts were administrated to diabetic rats in drinking water for five weeks. In series 2, the GI and II for a BFOMD, matching that in series 1, were determined to 92 and 64, respectively compared with GI = 97 and II = 65 in series 1. Bilberry tea – The reason why Bilberry tea is so effective in lowering blood sugar levels is because it contains something called glucoquinine which is a compound known for its ability to lower blood glucose levels.Another reason why Bilberry tea is such a good herbal tea for those with type 2 diabetes is because Bilberry is often used to treat eye issues such as diabetic neuropathy. The foot buffer is formulated to remove skin gently so it doesn’t have to be cut or filed. Insulin indices (II) for the FOMD and the BBFOMD were; II = 76 and 49, respectively. In fact, various research indicates that a direct relationship exists between lutein intake and pigmentation in the eye, and studies show that it may reduce blue light intensity by up to 90%.

Ingredients Two Capsules Contain: Chromium (as Chromium Chelidamate Arginate)* 100 mcg. Earlier studies have also shown that ANCs or their sources reduce blood pressure in rodent models of hypertension (10-12), but these studies did not utilize whole berries. The content of carbohydrates in the different products in the present study was similar, the amount of sugars being high (approximately 90%) and that of starch low. It also has shown anti-cancer properties in animal experiments. The observed GI value for the BBFOMD was thus lower than expected; but for the other drinks the calculated and determined GI values were in good agreement. The mending properties of garlic are known for quite a while, however its capacity to lessen glucose levels has been distinguished in the relatively recent past. Both the chromium and gymnema can improve blood sugar control.

The insulin-like properties were evident from enhancement of glucose uptake in differentiated muscle cells and adipocytes using an in vitro assay. I was stunned, after years and years of decreasing health, I finally knew. These results support our finding of a decreased acute glycaemic response with bilberry and show that bilberry (Vaccinium myritillus) may contain active molecules with potential anti-diabetic properties. Chromium appears to promote insulin sensitivity and improve glycemic control in many individuals.58 Additionally, chromium has been found to lower blood glucose levels, both at fasting and at two hours following a glucose challenge.59 Chromium also has been demonstrated to lower triglyceride levels and boost levels of HDL in patients with type II diabetes.59 Chromium thus helps to optimize both blood sugar levels and blood lipid profiles. Obesity and diabetes Spicy food and its ability to enhance energy expenditure have been known since the 1980’s. In addition, Pets Natural Choyce is an FDA-approved Food Facility, and all of our products are manufactured in a Pharmaceutical Graded, GMP-certified facility to guarantee the highest degree of consistency, reliability and potency. However, studies are lacking.


The insulin demand, if expressed as a relationship between insulinaemia and glycaemia (II/GI), was low, 0.62-0.68. Cardiovascular activity Black seeds extract is a potent cardiovascular protector. fruits prevent photo induced oxidation of low density lipoprotein cholesterol. Thus, studies with cereals [26], and certain fruits like mango, melon, pineapple, kiwi, apple and black grapes [19, 27] indicate good agreement between GI and II. In contrast studies with oranges and apples [28] as well as juice from these fruits [3, 29] were reported to display unexpectedly high insulin responses. It has the most attractive ingredients for an eye supplement: anthocyanins, DHA, and Lutein, and regarded as the best formulation eye supplement. Consequently despite extremely low GI (GI = 15-30) for regular and fermented milk, the II values were high (II = 90-98) [31], probably due to an insulinotrophic effect of whey protein [33].

One cause for the beneficial metabolic effects of a low glycaemic diet is probably a lower insulin response [34, 35], and increased insulin sensitivity [36]. All of our ingredients are Certified Organic, Kosher, or Responsibly Wildcrafted. The fermented oat meal base of the drinks, with sugars added to mimic the BFOMD was included as a reference drink (FOMD). A comparison between the FOMD and the BFOMD, gave no significant differences in glucose or insulin responses. Also, the insulin response to the FOMD (II = 76) was significantly lower than for white bread (II = 100). In a previous study with oats (oat porridge and oat flakes) no differences in glucose- or insulin responses were seen compared with a white bread [37]. This indicates that the fermentation process per se may decrease insulin response to oats.

It is also supported by a study with fermented whole grain oat showing a lower insulin response than would be expected from the glucose values [23]. However, the magnitude of insulin decrease in the post prandial phase was more pronounced when more bilberries were included in the meal. Of interest in this respect are results from an in vitro study evaluating the effect of fermented blueberry juice (intrinsic micro flora of blueberries) on glucose uptake and transport into muscle cells and adipocytes. Treatment of cells with fermented juice potentiated glucose uptake by 48% in C2C12 (mouse myoblast cell line) myotubes, and by 142% in 3T3-L1 adipocytes, whereas non fermented juice had no effect on glucose transport [38]. Treatment of cells with fermented blueberry juice was shown to activate AMPK. The authors thus suggest an insulin-independent pathway to be the mechanism for an increased glucose uptake [38]. A follow-up study in obese and diabetic mice showed that fermented blueberry juice decreased hyperglycaemia, in part due to increased adiponectin levels.

Bilberry jam and syrup may also be used. Acute glaucoma attacks can be triggered by stress or dilation of the pupil for long periods of time. However, insulin responses were significantly lower, or close to being significantly lower for the drink with rose hip (RFOMD) (P = 0.0673), and for all fermented test drinks whether containing bilberries or not. Whether the low insulin demand (II/GI) shown in the present study could be an effect of fermentation of bilberries is currently under investigation. All tested drinks had a low pH, or about 3 for the bilberry containing drinks, and about 4 for the fermented oat meal drink (FOMD). Krill oil also contains high-quality, animal-based omega-3 fat in combination with naturally-occurring astaxanthin. a lowering of the rate of gastric emptying [39].

However, such a mechanism should preferably affect both blood glucose and insulinaemia to a similar extent. Berries like bilberries and blueberries are known to be a rich source of bioactive molecules like phenolic and antocyanin contents [40] and phenolic acids [41]. Besides that they both are powerful antioxidants they may also exert effects on other important biological systems as glucose- and insulin response. Bilberries mixed with blackcurrants, cranberries and strawberries (150 g), other berries rich in antocyanins, have recently been shown to decrease the peak glucose increment of 35 g sucrose in healthy subjects [18]. Also in type-2 diabetic mice, anthocyanins in bilberry have been suggested to reduce blood glucose levels and enhance insulin sensitivity [16]. Water soluble polyphenols isolated from cinnamon has been shown to have strong insulin-enhancing activity on cultured fat cells in vitro, [42]. Also, when tested in healthy subjects, cinnamon (3 g) added to a rice pudding (300 g) was shown to reduce post prandial serum insulin, but not glucose, levels compared to a rice pudding without cinnamon [25].

It is impossible to draw any conclusions regarding the effects of the antocyanins and/or polyphenols present in the oat meal based fruit drinks (RFOMD, BFOMD, BBFOMD) in the present study. However, it cannot be excluded that such components might have contributed to the low insulin demand seen after the fermented oat meal drink added with bilberries.

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[ Diabetes Type 1 ]

Nutrition Journal

Today’s overweight children are more likely to become tomorrow’s chronically ill adults. Despite this trend, population-based studies suggest that rates of T2D among children have not yet increased substantially, which may reflect the latency period between the onset of obesity and the development of T2D, which can last upwards of 10 years of more. In Thailand, the prevalence among 6- to 12-year-old children increased from 12.2 to 15.5% over a 2-y period from 1991 to 1993.1 While a recent report suggested that one in four children in the United Kingdom are either overweight or obese.2 The prevalence of obesity among children aged 2 to 10 has increased from 9.9% in 1995 to 13.7% in 2003, with obesity levels similar in both genders. This number has actually tripled in the past 30 years. Sport NZ and Regional Sports Trusts will refocus some of the KiwiSport Regional Partnership Fund to provide more sport opportunities for young people in communities where participation rates are low and the risk of poor health is higher. Orthopedic Complications: Among growing youth, bone and cartilage in the process of development are not strong enough to bear excess weight. Adjustment for other perinatal and socioeconomic factors did not alter these associations.

Children and adolescents with a BMI between, at, or above the 85th percentile, and lower than the 95th percentile, are considered overweight. For example, an overweight boy who develops type 2 diabetes while a teenager and is left untreated will likely develop health problems with his heart, eyes, kidneys, and feet by the time he reaches his early 30s. In many Western countries, the last two decades have seen a drop in mortality from coronary heart disease and stroke, attributed to reductions in the prevalence of cigarette smoking, favorable changes in blood cholesterol and blood pressure, and improvements in treatment.5 Diminishing exposure to other major risk factors, through lifestyle changes and treatment patterns, might limit the adverse cardiovascular effects of obesity, as appears to be happening in the US.6 It is possible, however, that rising levels of obesity, type 2 diabetes, insulin resistance and metabolic syndrome components will reverse the current favorable mortality trends. The same pattern was seen for the prevalence of BMI > 95th percentile (2.9, SD = 0.1 vs. AAP’s guidelines encourage healthcare providers to recommend that patients participate in moderate to physical exercise for one hour each day, that nonacademic TV viewing be limited to two hours a day or less and to advise parents not to have TVs or video screens in children’s bedrooms. In Saudi Arabia, one in every six children aged 6 to 18 years old is obese [ 7 ]. Rates ranged from highs of 20.6 percent in Alaska and 20.1 percent in Virginia to lows of 8.9 percent in Colorado and 8.7 percent in Utah, in 2012.

Children who don’t get enough sleep at night are more likely to become overweight or obese. In addition, psychological disorders such as depression occur with increased frequency in obese children [10]. Overweight children followed up for 40 [11] and 55 years [12] were more likely to have cardiovascular and digestive diseases, and die from any cause as compared with those who were lean.

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[ Diabetes Type 1 ]

Nutrition Journal

It’s hard to see where the headline’s over-excited promises of weight loss or reduced hunger come from. With the majority of Americans eating more and more snacks, it’s a great thing to find a snack that doesn’t result in weight gain and that also provides nutritional benefits. Nuts – Although these tend to be high in fat, it is the good kind of fats, which can actually lower insulin resistance, which means your cells will be more sensitive to the insulin your body produces which will more effectively lower your blood sugar. While most of us think of fiber as primarily boosting digestive health, fiber has additional evidence-based benefits, including maintaining a healthy weight, and lowering the risk of diabetes, heart disease, and some cancers. It appeared recently in the Journal of the American College of Nutrition. Because a calorie is not a calorie. One 23-almond serving packs 13 grams of healthy unsaturated fats, 1 gram of saturated fat and no cholesterol or salt.

Oh, and 15 gr. It’s a large chain of food stores that carry some organic products. Unchewed nuts are hard on the digestive tract. Almonds are also sometimes used in cakes, biscuits, bread, chocolates, ice cream, and certain liqueurs (such as Amandine). Five published randomized cardiovascular trials have shown that pistachios promote heart-healthy blood lipid profiles. Macro- and micronutrients, fiber content, and other components of the diet modulate meal-induced insulin secretion through changes in gastrointestinal transit time and nutrient absorption rates. Eating almonds before or after a meal is a great way to stabilize your blood sugar levels and is recommended for both, diabetic and non-diabetic people.

Drain the water, peel off the skin and store them in plastic container. Phytic acid also blocks the uptake of essential minerals such as calcium, magnesium, copper, iron and zinc. For example, all of our patients were receiving multiple risk-reduction therapies and had well-controlled lipid profiles at baseline. The discrepant results might also reflect differences in the nutrient content of the various tree nuts; e.g., walnuts contain more polyunsaturated fats, including α-linoleic acid, than MUFA compared to other tree nuts. Some Jif® Brand peanut butters are also made with sugar. The effect of chronic consumption of almonds and other tree nuts on blood biomarkers of CVD have been demonstrated, although the results are mixed with regard to individual biomarkers. But consumers should be aware that gorging on the nuts is not to be advised.

The benefits of almonds on the lipid profile of healthy adults or those who have hypercholesterolemia, dyslipidemia, and/or prediabetes have been reported in several studies [28–33]. Since I stopped using almond milk my numbers have gone up a bit. [34] found that almond consumption at 37 or 73 g/day for 4 weeks increased oleic acid and MUFA content in serum TG and non-esterified fatty acid fractions. Jenkins et al. [16] extrapolated from their dose–response study to suggest that each 7-g portion of almonds would induce a 1 % reduction in LDL-C. In contrast, we did not find that the addition of almonds to the NCEP step 1 diet affected TC, TG, HDL-C, LDL-C or small density LDL-C. However, as the lipid profile at study baseline in our subjects were being maintained within normal ranges by statins and/or the NCEP Step 1 diet, it seems unlikely that any single food would enable a further significant improvement.

Inflammation plays a critical role in the risk for and progression of CVD such that inflammatory biomarkers like CRP and IL-6 are generally recognized as independent predictors of atherosclerosis [35–37]. We don’t know whether the small differences they found would have any effect on human health. Jiang et al. They have cholesterol lowering and anti cancer properties as well. Consistent with this observational data, we previously found that almonds decreased IL-6 and CRP, and TNF-α in Chinese patients with type 2 diabetes but did not affect ICAM-1 or VCAM-1 [40]. Rajaram et al. We controlled for poverty, urbanization, aging, and most important, obesity and physical activity.

In contrast, Damasceno et al. I didn’t eat any side dishes with any of these meals. Saturday January 1, 2011, 6:57 pm I was thinking my Sis-in-laws Dad grew almonds.. Almonds should not be taken on an empty stomach , it should be accompanied with fruits or milk. It is noteworthy that the concentration of CRP, IL-6 and TNF observed in this study appeared to be slightly larger than the values found in Chinese patients with type 2 diabetes [27] or coronary heart disease [42] and in the prospective Multi-Ethnic Study of Atherosclerosis [39]. I know they have sugar, but a few grams or less a day is not going to cause a major problem provided you’re eating a healthy whole food diet as opposed to processed foods (which are loaded with hidden fructose). Also, the null effect may be attributed to the direct or indirect anti-inflammatory effects of multiple medications taken by the patients.

Similar to the slight improvement in VCAM-1, urinary excretion of NO tended to increase with the ALM diet. These trends suggest a possible modest benefit of almond intake on endothelial function in CAD patients, so further research on this potential benefit is warranted. Almonds are a good source for a number of nutrients, with 85 g providing >10 % of the daily value of many vitamins (vitamin E, riboflavin, niacin, thiamin, and folate), minerals (calcium, copper, iron, magnesium, manganese, phosphorus, potassium, zinc), and fiber as well as arginine and oleic acid [43]. In addition, 85 g almonds contain 111 mg β-sistosterol, 9.3 mg flavonoids, and 156.5 mg proanthocyanins [44]. Relative to the CON diet, the ALM diet had a more positive impact on nutritional quality by increasing intake of calcium, magnesium, choline, and fiber above recommended values. The intake of these nutrients were below either the EAR or RDA when the subjects were consuming CON diet. These results are consistent with Jaceldo-Siegl et al.

[45] who found the addition of 52 g/day almonds to the habitual diets of healthy men and women for 6 months significantly increased their intakes of MUFA, PUFA, fiber, vegetable protein, vitamin E, copper, and magnesium and decreased the amount of trans fatty acids, animal protein, sodium, cholesterol, and sugars. Consumption of dietary polyphenols is associated inversely with the risk of CVD and cancer [46–48]. As almonds contain an array of polyphenols, particularly proanthocyanins, they can be part of recommended guidelines for healthy diets rich in plant foods. The study participants were patients with angiographically proven CAD and were taking on average 8 medications daily. Their polypharmacy regimen remained stable and effective during the 6-weeks almond intervention, suggesting intakes at 85 g/day are absent any indication of untoward drug-food interactions. Importantly, the change in the profile of nutrient intake during the ALM phase matched well general dietary recommendations to reduce the risk of CVD. It is also noteworthy that even though the ALM diet increased the percent of total calorie intake from fat from 29.1 to 44.4 %, there was no adverse effect on the lipid profile.

These results are consistent with the favorable effect of almonds on lipid profiles reported by others [49]. Our study had several limitations. The study duration of 6 weeks for each arm is a relatively short period to affect some biomarkers of CVD risk and progression, so a longer intervention or larger sample size may have resulted in a statistically significant reduction in plasma VCAM-1 and increase in urinary NO. Conversely, while we found no untoward impact of the ALM diet on concurrent drug therapy, we cannot exclude the development of such interactions over a longer period. It is possible the study design, including a 6-weeks run-in period on the NCEP Step 1 diet that was then continued throughout both study arms and the 4-weeks washout, may have masked an impact of the almond intervention. Similarly, efficacy of the polypharmacy regimens of the subjects may have largely achieved the maximal benefit possible in these patients on the outcome parameters of vascular reactivity, inflammation, and oxidative stress. Finally, the study might be underpowered for both the primary and secondary outcome measures since the power calculation was performed based on the improvement in FMD.

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[ Nutrition ]

Nutrition Journal

The vegetable goes by many names. However, the mounting research into bitter melon’s unique therapeutic properties appears to be yet another testament to the advantages of certain natural therapies over many conventional drugs. Because it is the root cause for many diseases and would force the individual to avoid all his favorite dishes. Professor Philip Home answers a few questions related to diabetes and throws some light on how Novomix 30, a drug founded by Novo Nordisk, a health care company based in Denmark is revolutionary in treatment of diabetes… Renal hypertrophy was higher in diabetic controls and bitter gourd supplementation, partially, but effectively prevented it (38%) during diabetes. In Type II (non-insulin dependent adult-onset diabetes or NIDDM), the pancreas produces insulin but is insufficient for reducing the blood glucose levels to normal. Bitter melon has the ability to increase the insulin sensitivity in our body.

From nutrition, water 93.4g in every 100g gourd, carbohydrate 3.5G, 1.4g 0.1g protein 1g, fat, dietary fiber, and sodium, calcium, iron and other trace elements and vitamins, VB1, Vc content of which ranks first in the melon. Er heeft zich inmiddels een teler uit Almere gemeld die de Bittergourd graag wil gaan verbouwen. Studies have shown that insulin encourages pancreatic cancer cells to grow in a dose-dependent manner, since bitter gourd has been shown to help regulate insulin levels, this could help prevent pancreatic cancer over the long-term. Swai, C.J. Bitter gourd leaves contain many bioactive constituents and are full of medicinal properties. Ming-Shi Shiao of the Department of Biomedical Sciences, Chang Gung University, Taiwan, said that consuming 500 gm to 1,000 gm of bitter gourd per week would check diabetes, while the general consumption was only 100 gm per week now. Fortunately, a 19% decrease in the MetS incidence rate was observed despite that only 42 subjects were recruited and 4 (9.5%) of them have dropped out.

In addition to the individual differences in MetS risk factors, the heterogeneity of our study subjects also arisen from the great range of their ages (23-63 years) and BMI (22.3-45.2). As such, their treatments aim to break down the quick metabolism of cancer cells with minimum damage to surrounding healthy tissue, which, as it turns out, can be a tricky thing. Further research is required to understand how these compounds actually work. But consuming the vegetable is a tough job for some people. All these heterogeneities should be avoided if a randomized controlled trial is to be carried out in the future. The regulation of glucose metabolism by BG or it extracts/components has been extensively reviewed and various active compounds and action mechanisms have been proposed [3–5]. Patients are recommended to include the vegetable in their diet, either as a stir-fry, juice or in capsule form.

• It keeps your scalp healthy. Recently, cucurbitane-type triterpenoids isolated from BG were shown to increase glucose transporter 4 translocation through activation of AMPK [27], inhibit α-glucosidase [28], and modulate insulin secretion activity [29]. 9c,11t,13t-conjugated linolenic acid [30] and momordin [31] from BG were noted to activate PPAR α, γ and PPAR β/δ respectively. Start growing bitter gourd in your own vegetable garden asap and should you need any help in organic home gardening, get in touch with Vandana at 9535025938 or send in a mail at vandana@artyplantz.com. In addition, PPARβ/δ has been shown to play a critical role in the body fat reduction in an animal model [33]. You can grow bitter gourd in your kitchen garden or in containers in your balcony. The Hualien No.4 WBG used in this study is a hybrid variety of WBG being selected for its high PPAR activating activity.

Other proposed mechanisms for actions of BG include stimulation of pancreatic insulin secretion [35], decreased hepatic gluconeogenesis, increased hepatic glycogen synthesis, metformin- and sulfonylurea-like glycemic control activities [5, 36]. Almost all the human studies associated with metabolic disorder using bitter gourd were focused on controlling type 2 DM [3]. There are a number of ways you can easily incorporate bitter melons into your diet. The research and information contained in this article was accurate at the the time of publication but may have been updated since the date of publication. It promotes the growth of useful muscles and energizes the body. This trend of change in the waist circumference was similar to the decline in the incidence rate of MetS, despite that lowering of waist circumference to less than 90/80 cm were not the main contributors for subjects that showed a release from having MetS after three months of BG supplementation. Abdominal obesity is well recognized as a potential etiologic factor of MetS [38]; hence, reverted central obesity is of significance for overall MetS management.

This finding from our study is particularly important for Asians, a population that is likely to have metabolic obesity [39]. In general, lyophilized WBG powder capsule preparations in our study were well tolerated. There were few adverse events and these were generally mild. In previous human trials, the most commonly reported side effects are abdominal pain and diarrhea [24]. Our study showed that adverse effects were mostly moderate, including one and two subjects with abdominal pain and bloat respectively. To our knowledge, this is the first human trial to evaluate the effects of WBG on MetS. Bitter gourd plant produces both male and female flowers.

The relatively small sample size and substantial heterogeneity of the studied subjects limited our power to detect differences in many metabolic endpoints. This was an uncontrolled trial, so we cannot exclude the placebo effect. Nevertheless, after discontinuing the supplementation agent, our subjects were followed up for MetS over an additional three-month period. On the other hand, a recent study demonstrated that taking dietary supplements may create an illusory sense of invulnerability that disinhibits unhealthy behaviors because such supplements are perceived as conferring health advantages [40]. This might also be a concern as we did not monitor diets and other life-style factors of our subjects throughout the study period. It  is also a rich source of the vitamin C, B1, B2 and B3.

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