Explain the pathophysiology of diabetic peripheral neuropathy (DPN). Diabetic people no longer produce insulin or their bodies no longer react to it or react inadequately. Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy; mononeuropathy; mononeuropathy multiplex; diabetic amyotrophy; a painful polyneuropathy; autonomic neuropathy; and thoracoabdominal neuropathy. RESEARCH DESIGN AND METHODS Adults aged ≥40 years (n = 2,514) were evaluated in the 2001–2004 National Health and Nutrition Examination Survey for clustering of two or more cardiometabolic characteristics, including elevated triglycerides or plasma glucose, low HDL cholesterol levels, increased waist circumference, or hypertension. The “moving wall” represents the time period between the last issue available in JSTOR and the most recently published issue of a journal. T2-weighted fat saturated cross sectional SPAIR MR Image (0.3 × 0.3 × 3 mm3) of (B) a diabetic type 2 patient with neuropathy and (C) a diabetic … The participants walked at their own pace along the walkway and stopped in front of a marked stopping line while kinetic and kinematic data were recorded.
Diabetes mellitus (DM) is a chronic disease of hyperglycemia associated with metabolic syndrome, which is characterized by insulin resistance . Diabetic peripheral neuropathy development was significantly more frequent in participants presenting with cardiovascular disease at baseline (P=0.01). The relationship between glycemic variability and diabetic peripheral neuropathy in type 2 diabetes with well-controlled HbA1c. Nerve conduction studies are considered by many as the “gold standard” for nerve damage and the most consistent indicator of (sub-)clinical neuropathy . 2014;6(1):139. Wu J, Zhang X, Zhang B. Efficacy and safety of puerarin injection in treatment of diabetic peripheral neuropathy: a systematic review and meta-analysis of randomized controlled trials.
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Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. Although each of these components in itself is a risk factor for cardiovascular disease and other related outcomes such as PVD, their aggregation or “clustering” may result in a greater overall disease risk (14,15). 2011;343:d4002. Acker K, Bouhassira D, Bacquer D, Weiss S, Matthys K, Raemen H, et al. Prevalence and impact on quality of life of peripheral neuropathy with or without neuropathic pain in type 1 and type 2 diabetic patients attending hospital outpatients clinics. Subsequently, a composite score has been introduced for quantitative analysis of the results of NCS . 2009;35(3):206-13.
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