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Medication Adherence With Diabetes Medication: A Systematic Review of the Literature. – PubMed


2 – Centers for Disease Control and Prevention. Jha (ajha{at}hsph.harvard.edu) is an associate professor of health policy at the Harvard School of Public Health and an associate professor of medicine at Harvard Medical School, in Boston, Massachusetts. This study attempts to improve understanding of both patient and provider factors involved in lack of adherence to treatment in diabetic patients by using the conceptual model of attachment theory. This number is projected to increase substantially in the next 15 years. In addition, parents’ and youngsters’ perceptions of family cohesion predicted improved adherence as well as overall higher levels of patient adherence. We obtained a complete medication profile of all participants and calculated the number of prescribed drugs and the adherence indices (AI) for oral blood glucose, blood pressure and cholesterol lowering drugs. On average, less than 40 percent of individuals with Type 2 Diabetes globally are achieving optimal levels of adherence (the extent to which a patient follows the prescribed interval and dose of a medicine regimen) and persistence (the time from initiation to discontinuation of a therapy).

In contrast, those randomized into the IEAI group received a 6-month behavioral intervention consisting of a series of group and individual sessions. If left untreated, diabetes can lead to severe health problems and complications, such as heart disease, stroke, vision loss and amputation. Our findings regarding barriers with significant effect on insulin adherence may be useful to identify patients at risk for low compliance, and to guide the design of proper strategies to improve adherence and the consequential clinical outcomes. Health professionals working with individuals with diabetes (eg, diabetes educators) are in a key position to assess risks for nonadherence, to develop strategies to facilitate medication taking, and to provide ongoing support and assessment of adherence at each visit.

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