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Ebola Infection and Diabetes Mellitus

Epidemiologic studies have suggested possible atherogenic roles for such pathogens as Chlamydia pneumoniae, Helicobacter pylori (Hp), cytomegalovirus, and herpes simplex virus. The purpose of the study was to determine the demographic characteristics of diabetic burn patients and their rate of community-acquired and nosocomial infections. We accessed the Healthcare Cost and Utilization Project’s Nationwide Emergency Department Sample database and the Nationwide Inpatient Sample database to perform a retrospective analysis on diabetics presenting to the emergency department or hospitalized for infection management from 2006 to 2011. Empirical and epidemiological studies both point to antimicrobials against gram-positive organisms as those most strongly associated with T1D.2 A definitive interpretation of the study by Beyerlein and colleagues is difficult without adjusting for this confounder. Some large population-based observational studies have reported strong associations between higher HbA1c and infection risks for both type 1 and type 2 diabetes. Mice inoculated with the IL-4 expressing CVB3 chimeric strain were better protected from T1D onset than were mock-infected control mice despite intraislet viral replication. These series reported an infection rate of 5.5 to 20% and contained small cohort of patients.

Women’s narratives revealed more social suffering as well as more mental distress and somatic symptoms, including multi-morbidities, than men’s. Missed insulin treatments or inadequate insulin therapy can leave you with too little insulin in your system, triggering diabetic ketoacidosis. Most of these papers concluded that standard antibiotic therapy allows a significantly lower H. CONCLUSIONS We demonstrated for the first time that H. The team compared the risk of infection when taking into account different types of diabetes, how long patients had been diagnosed with the condition and other associated complications of living with diabetes. However, there are some previous reports mentioning the value of blood glucose determination in Ebola virus infection. Reilly reported in her poster.

In: Mandell GL, Bennett JE, Dolin R, editors. There is a strain of staph that is resistant to antibiotics. Diabetes in general is a risk factor for surgical site infection (SSI) post-surgery. The increased blood glucose level is observable and this is a usually forgotten problem (4). Arsand et al. noted that hyperglycemia might be an early clinical observation of Ebola virus infection during the outbreak (4). In a recent report by Brizendine, the increased blood glucose level was also reported in the patient infected with Ebola virus disease (6).

Nevertheless, not only increased but also decreased blood glucose level can be expected. Since the gastrointestinal problem, especially for diarrhea, is common in Ebola virus disease, the decreased blood glucose level can be expected. The developing insulitis and concurrent beta cell killing eventually result in T1D onset starting to occur by 12–15 weeks of age, 70–100% of female NOD mice develop T1D by 30–40 weeks of age (Tisch et al., 1999 and Tracy et al., 2002). The point-of-care testing blood glucose monitoring could be useful tool for monitoring purpose (7). The importance of maintain normal glucose level in outcome of the patients with Ebola virus disease should be mentioned since the extreme fluctuation of blood glucose level can be the serious comorbid condition that superimpose the critically ill condition of the patients. http://www.uptodate.com/home. Additional study on the severity and clinical course of Ebola virus infection in such cases should also be investigated.

These data is helpful for summarization on the unknown relationship. Nevertheless, it is generally recommended that a patient with diabetes mellitus might have a high vulnerability to the infection. These patients should be especially cared and prevented for the infection. It is very interesting to see the connection between Ebola infection and diabetes mellitus. Atherton JC, Blaser MJ. Hence, it is not possible to establish the direct relation of Ebola infection and diabetes until the detailed analysis. After going through the present article “Ebola infection and diabetes mellitus-short information”, the authors would like to raise the following concerns [a].

Study to assess the prevalence of diabetes among patients infected with Ebola [b]. Severity and clinical course of Ebola infection in diabetics, and [c]. Is there high vulnerability for diabetics to Ebola? Regarding [a] the possible method is to look for Ebola seropositivity among diabetics. The screening will be expensive and is not going to help anybody. Regarding [b]&[c] it may be noted that defense mechanism of body to infection tend to fall when FBS exceed 210 mg% and hence blood sugar estimation is recommended whenever we are dealing with an infection especially when the incubation period of the disease is smaller as in Ebola. Besides these aspects, there is another question to be answered- Is there definite interaction between diabetes and Ebola?

It is still the myth that “do both these situations worsen each other?” Such mutual worsening occurs when there is sharing and synergism of pathophysiology like elevation of cytokines like IL-6. In conclusion, Ebola infection is a major public health problem, which needs more investigation about the prevention and control of the disease, as well as the diagnosis and treatment of the disease. The relationship between Ebola and diabetes is a forgotten topic and there is need to focus on this question.

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