It generally is accepted that a diet high in fiber, particularly soluble fiber, is useful in the management of the plasma glucose concentration in individuals with diabetes. We examined possible interactions for both individual SNPs, as well as combinations of SNPs by calculating a GRS. patients: One hundred twenty-eight subjects with type 2 diabetes mellitus and 50 age-matched normal control subjects without glaucoma or glaucoma-suspect. The dietary intake was estimated from a self-administered food frequency questionnaire, and insulin resistance was estimated using the homeostasis model assessment of insulin resistance (HOMA-IR). However, research shows that total dietary fiber consumption contributes to a number of unexpected metabolic effects including improved insulin sensitivity, secretion of certain gut hormones, and effects on various metabolic and inflammatory markers associated with metabolic syndrome (1). High-carbohydrate, high-fiber diets providing 55% to 60% of energy as carbohydrates, 15% to 20% as protein, and 20% to 25% as fat and including 50 gm or more fiber daily hold the most potential for long-term use. The question is this: How many times a day should I poop?
In contrast, neither a high intake of fruit fibre (RR 0.96), nor a high intake of vegetable fibre (RR 1.04), were appreciably associated with type 2 diabetes risk; these estimates had sufficient precision to exclude RR reductions of ~15% with a high degree of confidence.