[ Nutrition ]

Current recommendations on managing tuberculosis patients with diabetes & its epidemiology


Glucose tolerance was assessed, according to WHO diagnostic criteria, in 506 consecutive African patients admitted with sputum-positive pulmonary tuberculosis to the tuberculosis wards of Muhimbili Medical Centre, Dar es Salaam. We conducted a retrospective cohort study of patients with active, culture-confirmed tuberculosis (TB) in Maryland to determine the impact of DM on TB treatment outcomes. Using Poisson regression analysis, we estimated TB incidence in individuals with DM vs. We recently reported that smear-positive TB was associated with a 10 kg weight loss, which was both reflected in large deficits in arm fat area and especially arm muscle area [7], suggesting that nutritional support to facilitate optimal recovery of lean body mass is needed during the treatment. The series on TB and diabetes published in The Lancet Diabetes & Endocrinology today, has papers contributed by the World Health Organization (WHO). Diabetes was most prevalent in the 45-55 year age group, and increasing weight, BMI and waist circumference were associated with diabetes. Diabetes mellitus may adversely affect the outcome of tuberculosis treatment.

A persuasive advocacy report will be elaborated, including evidence from pilot projects and recommendations from literature reviews. The prevalence of diabetes globally is projected to rise from the current estimate of 150million to 200million in 2010 and to 300million (5.4%) in 2025. Today with type 2 now accounting for 90 to 95% of all diabetes we are “re-discovering” this association [11–21]. The increasing diabetes prevalence may be a threat to TB control. For additional information on TB in the Pacific region, contact Ms Kerri Viney at  Cette adresse email est protégée contre les robots des spammeurs, vous devez activer Javascript pour la voir.

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