[ Diabetes Type 1 ]

Comparison of fluoxetine and paroxetine in type II diabetes mellitus patients. – Abstract


Cerebral dysfunctions, including a high incidence of depression, are common findings in human type 1 diabetes mellitus. Blood tests may be needed to check for unwanted effects. Blood glucose level, glycated haemoglobin, grip strength, pain sensitivity and threshold in diabetic rats were measured at the end of 9 weeks. En hoe staat het met antipsychotica? There was also a significant fall in carbohydrate intake after 3 months (30 g day−1) and 6 months (23 g day−1) on fluoxetine as well as a significant fall in carbohydrate intake expressed as a percentage of the total daily energy intake; 5.9% at 3 months, 6.1% at 6 months, and 4.0% at 9 months. Inclusion criteria were unsatisfactory glycemic control, defined as GHbA1c ≥ 6.5% or fasting blood glucose ≥ 7.0 mmol/l, and mild depression, defined as a score between 2.5 and 12 on the MADRS, i.e. There was also found loss of pain perception in diabetesrats which measured using hot plate and tail flick methods.

However, clinical and experimental trials have demonstrated that SSRIs may affect the blood glucose levels in various ways, by causing hypoglycemia [2], increasing insulin sensitivity [3], or aggravating blood glucose levels after glucose overload [4]. This triggered an apoptotic process, manifested by enhanced caspase 3/7 activity, which resulted in β cell death. There is need for further and longer-lasting monitoring studies with more patients in order to determine whether there is any difference in terms of their effects on glycemic control.

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