Statins are the most commonly used cholesterol-reducing drugs. When blood tests reveal high LDL cholesterol levels, doctors tend to reflexively reach for their prescription pad for the quick-fix mainstream medicine solution — statin drugs. The principal aim of the present study was to assess the effect of CoQ10 supplementation on glycemic control and oxidative stress in type 2 diabetic patients. Anti-inflammatory effects of fish oil may reduce symptoms of rheumatoid arthritis, according to a review of previously published research that appeared in the June 2012 issue of the “British Journal of Nutrition.” Authors found that fish oil consumption caused a decrease in levels of the pro-inflammatory omega-6 fatty acid called arachidonic acid and increased activity of immune system signaling molecules that inhibit and resolve inflammation. The mean insulin sensitivity and total antioxidant capacity (TAC) concentration significantly increased in the Q10 group compared to the placebo after the trial (P < 0.05). Schachinger V, Britten MB, Zeiher AM. However, the role of ANT-mediated mitochondrial uncoupling was beyond the scope of the present study.
For ejection fraction at rest (384 patients) the weighted mean difference showed a trend in favour of CoQ10 of 1.9% (95% confidence limits – 0.13% to 3.9%). The hypotensive effect of CoQ10 in hypertensive individuals has been established consistently in level 1-4 evidence. We normally make CoQ10 and derive very little from diet. It also regenerates Vitamin E and Vitamin C (which are antioxidants) to their oxidized form. Nonetheless, depending upon your circumstance it is probably worthwhile having a conversation with your doctor about it, particularly if you are at risk for heart disease. As you will see below, there are few know side effects from taking it. Let’s take a closer link at the link between CoQ10 and diabetes health.
It could improve LVDD in diabetes by reducing myocardial free fatty acid and triglyceride delivery, thereby decreasing formation of lipid intermediates and oxidant species that promote myocyte apoptosis and fibrosis (1). Biomed Aging Pathol 2012;2:157-72. Free radicals are a byproduct of our internal energy production and are even stronger in pollution, radiation, etc. Type 2 diabetes increases the chance of a heart attack; it may kidney damage, eye problems, foot and skin complications, and more. Moreover, this study was very small, looking at only 9 people with type 2 diabetes. There is no Recommended Daily Allowance (RDA). There is also no upper limit dosage set for CoQ10, but at least one study stated that you should take no more than 1200mg per day.
However, some people taking as little as 100mg per day have reported mild insomnia. Other side effects that have been reported include: light sensitivity, heartburn, nausea, fatigue, dizziness, irritability, headache, and rashes.