To determine the effects of chromium (Cr) supplementations on oxidative stress of type 2 diabetes and euglycemic (EU) subjects, adult having HbA(1C) values of 8.5% (severely hyperglycemic, SH) were supplemented for 6 months with 1000 microg/day of Cr (as Cr yeast) or with a placebo. In the present studies, we test the hypothesis that chromium supplementation raises serum chromium levels and correspondingly improves insulin sensitivity. For non-prescription products, read the label or package ingredients carefully. Control and verum periods were each 2 months in duration. And the good news is that chromium might help reverse type 2 diabetes, insulin resistance, blood sugar disorders, and metabolic syndrome (also known as Syndrome X). Chromium is a mineral and is considered an essential trace element because microscopic quantities are required for good health. The supplements decreased the expression of NF-κB in diabetic rats (P< 0·05). Type 2 diabetes Higher-dose chromium, carefully monitored, could help manage this condition. The FDA can only remove such products from the market later if problems happen to be detected. Research has also demonstrated chromium supplementation to be associated with an antidepressant effect as well as anti-diabetes effects.1 Hypochromia status is associated with lower glucose control and unfavorable lipid metabolism.1 Diminished chromium levels, as determined by scalp hair analysis utilizing spectrophotometry, can occur in patients with diabetes in comparison to patients without diabetes. Dietary chromium is poorly absorbed. A recent meta-analysis pooled the results of 41 studies and found that chromium supplements do appear to improve blood sugar control in people with type 2 diabetes, but the authors state that well-designed clinical trials are still required before any firm claims can be made.3 No benefits of chromium supplements on blood glucose have been found in people without diabetes. You can spend your money on chromium supplements, but even if it “works” and causes you to lose an extra 300 grams on the bathroom scale, it probably isn’t going to prevent a heart attack or cure your diabetes. In 2001, the daily dietary requirement for chromium was lowered in the United States.