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best use of medicine in pregnancy

Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk (1.6 to 1.7 times) of death compared to placebo (4.5% vs 2.6%, respectively). Patients with diabetes should be regularly monitored for worsening of glucose control; those with risk factors for diabetes should undergo baseline and periodic fasting blood glucose testing. The plaintiff, Cheyenne Beth Confer, says she was 15 years old when she was prescribed Abilify in May 2009. Cerebrovascular Adverse Events, Including Stroke: Increased incidence of cerebrovascular adverse events (e.g., stroke, transient ischemic attack), including fatalities, have been reported in clinical trials of elderly patients with dementia-related psychosis treated with oral aripiprazole. Your healthcare provider should check your blood sugar before you start receiving Abilify Maintena and during your treatment. Your healthcare provider should check your blood sugar before you start receiving ABILIFY MAINTENA and during your treatment. Signs and symptoms of NMS include hyperpyrexia, muscle rigidity, altered mental status, and evidence of autonomic instability (e.g., irregular pulse or blood pressure, tachycardia, diaphoresis, and cardiac dysrhythmia).

Additional signs may include elevated creatine phosphokinase, myoglobinuria (rhabdomyolysis), and acute renal failure. Doctors should specifically ask about the development of new or intense urges to gamble, have sex, shop, or binge eat. Tardive Dyskinesia (TD): The risk of developing TD (a syndrome of abnormal, involuntary movements) and the potential for it to become irreversible are believed to increase as the duration of treatment and the total cumulative dose of antipsychotic increase. She gained 30 pounds in six months and was diagnosed with diabetes. Prescribing should be consistent with the need to minimize TD. There is no known treatment for established TD, although the syndrome may remit, partially or completely, if antipsychotic treatment is withdrawn. Hyperglycemia/Diabetes Mellitus: Hyperglycemia, in some cases extreme and associated with ketoacidosis, coma, or death, has been reported in patients treated with atypical antipsychotics including aripiprazole.


Patients with diabetes should be regularly monitored for worsening of glucose control; those with risk factors for diabetes should undergo baseline and periodic fasting blood glucose testing. Use Abilify Maintena with caution. Patients who develop symptoms of hyperglycemia should also undergo fasting blood glucose testing. In some cases, hyperglycemia has resolved when the atypical antipsychotic was discontinued; however, some patients required continuation of anti-diabetic treatment despite discontinuation of the suspect drug. If your firm is interested in referring us a case or for us to send you a list of previous award judgments and/or average referral fees, please visit the Lawyer Referral section of our website. Weight Gain: Weight gain has been observed. Pathological Gambling and Other Compulsive Behaviors: Compulsive or uncontrollable urges to gamble have been reported with use of aripiprazole.

Leukopenia, Neutropenia, and Agranulocytosis: Leukopenia, neutropenia, and agranulocytosis have been reported. Patients with a history of clinically significant low white blood cell (WBC) count or drug-induced leukopenia/neutropenia should have their complete blood count monitored frequently during the first few months of therapy while receiving Abilify Maintena. No other studies have investigated this and it is therefore not yet clear whether there is a link between atypical antipsychotic use in early pregnancy and heart defects. Try to get into the habit of taking your doses at the same time of day each day, as this will help you to remember to take it. Relying on  short-term studies makes no sense because patients with depression, PTSD, and these other problems have those conditions for many years. Taken together, these studies do not prove that taking antipsychotics during early pregnancy causes birth defects in the baby. This medication should not be used if you have certain medical conditions.

pregnancy or plans to become pregnant. No increased risk of miscarriage in women who took aripiprazole in pregnancy was seen in either of the two small studies that have investigated this. However, more pregnant women taking aripiprazole need to be studied to confirm this finding. No increased risk of miscarriage was seen in any of three studies of pregnant women taking any antipsychotic. Some of the women in these studies were taking aripiprazole but were not studied separately so we do not know how this information relates specifically to pregnant women taking aripiprazole. No studies have specifically investigated whether women who take aripiprazole in pregnancy are at increased risk of stillbirth. Victims of type 2 diabetes caused by taking drugs such as Abilify, Seroquel, Risperdal, and Zyprexa, should consult with an experienced dangerous drug lawyer as soon as possible to learn their rights and to maximize their chance at recovery.

However, stillbirth rates need to be studied in pregnant women specifically taking aripiprazole before conclusions can be drawn. The single small study that has investigated this outcome suggested that aripiprazole use in pregnancy may increase the risk of preterm birth. Some, but not all studies of pregnant women taking any antipsychotic have shown an increased risk of preterm delivery. It is therefore not yet clear whether use of aripiprazole or another antipsychotic medicine in pregnancy could affect when a baby is born. More information on individual antipsychotics is needed.

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