Astaxanthin, a member of the carotenoid family, is a dark-red pigment which is the main carotenoid found in the marine world of algae and aquatic animals. Astaxanthin is a red-orange carotenoid pigment derived from microalgae, fish, and crustaceans that can prevent and even treat conditions that progress from the negative effects of oxidative stress and antioxidant deterioration. After 15 days, mice in each group were subdivided among 2 smaller groups and treated with ASX (2 mg·(kg body mass)–1) in olive oil for 45 days. While this may not seem like much, the average annual weight gain for adults is about two pounds, so the holiday season can account for almost half of yearly midlife weight gain.3 Gradual, creeping weight gain is perhaps the most important contributor to the development of metabolic syndrome. However, not all sources of soy are equal and there are a few soy lecithin side effects that you will need to be aware of. Three Dimensional structures of the proteins RHOD, BDNF were taken from the PDB databank and the ligands, Astaxanthin, Beta carotene were downloaded from Ligand database. Increased levels of free radicals are present in environmental pollutants, as well as from the reactions of engineered compounds in processed foods.
It occurs because of consistently high blood sugar, problems with the metabolism of carbohydrates, or limited release of insulin from the pancreas. The results also indicated that Astaxanthin significantly increased levels in blood plasma, and lowered liver and kidney weights as well. In support of strong anti-oxidant function within the body, astaxanthin administration has demonstrated statistically significant anti-oxidant capacity in humans as measured by decreased isoprostanes, decreased malondialdehyde (“MDA”) levels, increased total anti-oxidant capacity (“TAC”), and increased superoxide dismutase (“SOD”), as well as decreased lipid peroxidation. The following year, the company identified the Natural Energy Laboratory on the Kona Coast of Hawaii as an ideal spot to grow Haematococcus microalgae, from which astaxanthin is produced. Many studies support the strong influence of astaxanthin on mitochondrial functionality, as well as inflammatory and metabolic intracellular signaling in animals and in cell-based models. It’s a strong antioxidant and astaxanthin has many very potent physiological activities, such as antioxidant action [1,3], anti-inflammation , anti-high blood pressure , anti-diabetes , anti-obesity , anti-tumor and anti-cancer effects , mental improvement , improvement of age-related vision , and less eye fatigue or tiredness . This allows astaxanthin to neutralize singlet and triplet oxygen generated by UVA and UVB radiation and other sources, to bind to lipoprotein, an efficient transport vehicle, making it more bioavailable, and to increase immune system function, including heightened production of antibody-secreting cells and Interleukin 2 and suppression of Interferon-gamma.
Astaxanthin has been shown to be a very effective clinically validated remedy for all types of tendon, joint and muscle pain including arthritis and tennis elbow – eye, brain and skin health and provides numerous overall health benefits for athletes and others who seek a competitive edge. Localizes in the plasma, mitochondrial, and nuclear membranes; Scavenges or quenches the unwanted initiators and effectors of inflammation—reactive oxygen (“ROS”) and nitrogen species (“RNS”); and Demonstrates no evidence of the immunosuppressive effects of steroids or TNF-α inhibitors or off-target effects (e.g., receptor or pathway).